
Science
/science3527
Looking at the world as it is, unencumbered by how we want it to be. Proudly hosted by and co-modded by
a next state of quantum computing - the era of *efficient* Turing Machines? https://thegradient.pub/knocking-on-turings-door-quantum-computing-and-machine-learning/
This could be one of the biggest conceptual leaps that stems from AI
What happens if we replace the metaphor of DNA as a blueprint or a set of letters, to a full on generative model - like a variational autoencoder
The blueprint metaphor has got us this far. But now we need something with a much more flexible texture - that captures an expansive, emergent system which encodes endless possibilities.
https://osf.io/preprints/osf/r8z7c_v1
What happens if we replace the metaphor of DNA as a blueprint or a set of letters, to a full on generative model - like a variational autoencoder
The blueprint metaphor has got us this far. But now we need something with a much more flexible texture - that captures an expansive, emergent system which encodes endless possibilities.
https://osf.io/preprints/osf/r8z7c_v1
Great article on synthetic biology by @gmo
The industry feels like it's lost a lot of its lustre, but after reading this I feel a lot more hopeful about some of the amazing breakthroughs on the horizon and our potential "reconciliation with biology"
The industry feels like it's lost a lot of its lustre, but after reading this I feel a lot more hopeful about some of the amazing breakthroughs on the horizon and our potential "reconciliation with biology"
6015
Ayan
@gmo·3 days ago
Time for a Synbio Intervention (with love)
Take a deep dive with me and learn why “a cell is not a computer—a cell is a cell”
The bioengineering revolution isn’t dead. It’s just taking the long road.
https://open.substack.com/pub/editlife/p/synbios-reality-check
Take a deep dive with me and learn why “a cell is not a computer—a cell is a cell”
The bioengineering revolution isn’t dead. It’s just taking the long road.
https://open.substack.com/pub/editlife/p/synbios-reality-check
Latest drama out of the food science world:
Novo Nordisk announces project UPDATE to clarify the NOVA definitions of ultra-processed foods (a term coined by Brazilian professor Carlos Monteiro)
Monteiro sends back an open letter co-signed by 80+ scientists asking them to remove NOVA and UPFs from its title.
The food science world is now split into 2 camps, both arguing that the other position is anti-science.
https://x.com/NUPENS_USP/status/1894860514662203643
Novo Nordisk announces project UPDATE to clarify the NOVA definitions of ultra-processed foods (a term coined by Brazilian professor Carlos Monteiro)
Monteiro sends back an open letter co-signed by 80+ scientists asking them to remove NOVA and UPFs from its title.
The food science world is now split into 2 camps, both arguing that the other position is anti-science.
https://x.com/NUPENS_USP/status/1894860514662203643
Ok, this /science is pretty amazing 👇
https://warpcast.com/zahedtabnak.eth/0x205f3523 https://media.tenor.com/MFaypA9aSwIAAAAC/itsscience-ronburgundy
https://warpcast.com/zahedtabnak.eth/0x205f3523 https://media.tenor.com/MFaypA9aSwIAAAAC/itsscience-ronburgundy
media.tenor.com
478670
Zahed🎩
@zahedtabnak.eth·5 days ago
Scientists have managed to turn light into a solid material. This is a revolution in quantum physics.
https://www.newsweek.com/supersolid-light-physics-quantum-mechanics-2041338
https://www.newsweek.com/supersolid-light-physics-quantum-mechanics-2041338
I love this article about a new definition of what math is: https://davidbessis.substack.com/p/weve-been-wrong-about-math-for-2300
It is interesting because it merges philosophy and neuroplasticity, coming up with a great solution that resonates with me.
It is interesting because, for me, math has been about imagination. (how could you possibly define the nth dimension without imagination?) But for others, apparently, that's something terrible, and it doesn't mix well with what math is about.
Pinging @july @cassie @eulerlagrange.eth for their thoughts about this topic.
It is interesting because it merges philosophy and neuroplasticity, coming up with a great solution that resonates with me.
It is interesting because, for me, math has been about imagination. (how could you possibly define the nth dimension without imagination?) But for others, apparently, that's something terrible, and it doesn't mix well with what math is about.
Pinging @july @cassie @eulerlagrange.eth for their thoughts about this topic.
5925
Daniel Lombraña
@teleyinex.eth·4 days ago
Math is a human mental activity based on playing the “Game of Truth”: when we do math, we make as if notions had precise definitions that were perfectly stable over time, as if statements had binary “truth” values, as if one could play Lego and deduce new true statements from existing ones.

We've been wrong about math for 2300 years
A radical conceptualist take on the foundations of mathematics
davidbessis.substack.com
Math is a human mental activity based on playing the “Game of Truth”: when we do math, we make as if notions had precise definitions that were perfectly stable over time, as if statements had binary “truth” values, as if one could play Lego and deduce new true statements from existing ones.
I would have loved to have a physics teacher like him
https://www.instagram.com/share/reel/BAJxxjn_4W
https://www.instagram.com/share/reel/BAJxxjn_4W
A British research grup, aka Time Lords, are developing portable atomic clocks. They idea is to cool atoms to -273C degrees, so for example use them on plains to avoid GPS jamming.
The size of the clocks are too big, so they don't fit yet inside an airplane.
https://science.slashdot.org/story/25/03/05/1822239/could-new-clocks-keep-airplanes-safe-from-gps-jamming?utm_source=rss1.0moreanon&utm_medium=feed
The size of the clocks are too big, so they don't fit yet inside an airplane.
https://science.slashdot.org/story/25/03/05/1822239/could-new-clocks-keep-airplanes-safe-from-gps-jamming?utm_source=rss1.0moreanon&utm_medium=feed
Path integration formulation of quantum mechanics is a mind fuck
https://youtu.be/qJZ1Ez28C-A?si=8EmOy48IVRjJVrmk
https://youtu.be/qJZ1Ez28C-A?si=8EmOy48IVRjJVrmk
Scientists have genetically engineered mice with some key characteristics of an extinct animal that was far larger -- the woolly mammoth. This "woolly mouse" marks an important step toward achieving the researchers' ultimate goal -- bringing a woolly mammoth-like creature back from extinction, they say. "For us, it's an incredibly big deal," says Beth Shapiro, chief science officer at Colossal Biosciences, a Dallas company trying to resurrect the woolly mammoth and other extinct species.
https://science.slashdot.org/story/25/03/04/1624239/scientists-create-woolly-mice?utm_source=rss1.0moreanon&utm_medium=feed
https://science.slashdot.org/story/25/03/04/1624239/scientists-create-woolly-mice?utm_source=rss1.0moreanon&utm_medium=feed
New synthetic biological intelligence just dropped
“Outpaces silicon-based AI chips”
“We actually view it as a different form of life”
A lot to unpack here…
https://newatlas.com/brain/cortical-bioengineered-intelligence/
“Outpaces silicon-based AI chips”
“We actually view it as a different form of life”
A lot to unpack here…
https://newatlas.com/brain/cortical-bioengineered-intelligence/
I am normally quite wary of immune system hijacking therapies but this is very cool
https://www.synbiobeta.com/read/the-antibody-that-tricks-tumors-into-exposing-themselves
https://www.synbiobeta.com/read/the-antibody-that-tricks-tumors-into-exposing-themselves
Incredible breakthrough in next-gen DNA sequencing from Roche
At least 10x faster than current methods. High throughput. Cheaper reads. Game-changer for genomics
Great video explainer here:
https://youtu.be/G8ECt04qPos?si=2UWHc0ojQG_39-KK
At least 10x faster than current methods. High throughput. Cheaper reads. Game-changer for genomics
Great video explainer here:
https://youtu.be/G8ECt04qPos?si=2UWHc0ojQG_39-KK
I've seen a few viral posts recently pushing the link between race and traits like IQ
But as genomic research advances, it’s getting clearer that race is probably more of a social construct than a genetic reality
The real story is how outdated ideas keep trying to shape society when we have better ways to inform the stories we tell.
https://pioneerworks.org/broadcast/whats-real-about-race-rina-bliss
But as genomic research advances, it’s getting clearer that race is probably more of a social construct than a genetic reality
The real story is how outdated ideas keep trying to shape society when we have better ways to inform the stories we tell.
https://pioneerworks.org/broadcast/whats-real-about-race-rina-bliss
Quite excited about this out of MIT: a computer that fits into a single piece of thread weighing 5g!
Could be woven into clothing with all kinds of applications for bodily computing
Features analog sensing, digital memory, processing and communication
https://www.nature.com/articles/s41586-024-08568-6
Could be woven into clothing with all kinds of applications for bodily computing
Features analog sensing, digital memory, processing and communication
https://www.nature.com/articles/s41586-024-08568-6
This kind of information is freely available on the internet for everyone.
What a time to be alive.
https://www.youtube.com/watch?v=N5DAW8mkJ6Y
What a time to be alive.
https://www.youtube.com/watch?v=N5DAW8mkJ6Y
The Tesla of refrigerators is about to drop!
Refrigeration & AC account for ~20% of global electricity use and we now have kilowatt-scale efficiency and a legit alternative to vapour compression cooling!
paper: https://www.nature.com/articles/s41586-024-08549-9?linkId=13156497
Refrigeration & AC account for ~20% of global electricity use and we now have kilowatt-scale efficiency and a legit alternative to vapour compression cooling!
paper: https://www.nature.com/articles/s41586-024-08549-9?linkId=13156497
Taking DeSci to another level 👀…
557
pugson
@pugson·20:47 25/02/2025
which one of you haters is trying to kill me this time
AI bio models are on a serious upward trend
Open source ftw!!
https://x.com/nalidoust/status/1894381718750335354?s=46&t=Yro-7dBgnyXOS_0e3eMssw
Open source ftw!!
https://x.com/nalidoust/status/1894381718750335354?s=46&t=Yro-7dBgnyXOS_0e3eMssw
It is never bad to have another resource to learn stochastic calculus
https://jiha-kim.github.io/posts/introduction-to-stochastic-calculus/
https://jiha-kim.github.io/posts/introduction-to-stochastic-calculus/
Umm so we’re now turning our microscopes into 3D printers 💅🏽
Pre-print: https://www.biorxiv.org/content/10.1101/2025.02.20.639256v1
Pre-print: https://www.biorxiv.org/content/10.1101/2025.02.20.639256v1
“Similarly, Darwin laid out the evolutionary theory of biological organisms with no idea whatsoever what the mechanism of heritability was. As Darwin proved, an evolutionary theory can go extremely far without knowledge of the specific mechanism of inheritance.” - Julian Gough
According to a recent paper by an Israeli research team, it is possible to SCIENTIFICALLY predict the likelihood of divorce. Would you like to try it? https://phys.org/news/2025-02-divorce-interactions-cultural-personal-values.html
if an ant hits you going 100000000 mph would you die or would it not matter
Sad everyone knows about all the rare and crazy physics in the universe but not the most critical force in your daily life
Absolute banger of an intro. I was hooked.
“Don't like the F-word? Blame farmers and soft food.”
https://www.science.org/content/article/ancient-switch-soft-food-gave-us-overbite-and-ability-pronounce-f-s-and-v-s
“Don't like the F-word? Blame farmers and soft food.”
https://www.science.org/content/article/ancient-switch-soft-food-gave-us-overbite-and-ability-pronounce-f-s-and-v-s
Without checking the internet, what's the left hand rule?
So many insane innovations coming at us fast
I haven’t even had a chance to do a deep dive into Microsoft’s quantum computing chip
What do you mean you found a topological superconductor
What do you mean there is no peer reviewed scientific paper
What
Do
You
Mean
Cc. The physicists @aviationdoctor.eth
I haven’t even had a chance to do a deep dive into Microsoft’s quantum computing chip
What do you mean you found a topological superconductor
What do you mean there is no peer reviewed scientific paper
What
Do
You
Mean
Cc. The physicists @aviationdoctor.eth
In my opinion, the DeSci movement is largely made up of opportunistic business minds who tout decentralization but really just want to own a slice of the science pie sans offering any real innovation
However, in these strange times, a window for real change has opened—if they so dare 👀
https://idp.nature.com/authorize?response_type=cookie&client_id=grover&redirect_uri=https%3A%2F%2Fwww.nature.com%2Farticles%2Fd41586-025-00525-1%3FlinkId%3D13044544
However, in these strange times, a window for real change has opened—if they so dare 👀
https://idp.nature.com/authorize?response_type=cookie&client_id=grover&redirect_uri=https%3A%2F%2Fwww.nature.com%2Farticles%2Fd41586-025-00525-1%3FlinkId%3D13044544
tune in to hear about decentralized science from farcaster folks!
https://x.com/BlackFlagDAO/status/1892272691278721106
https://x.com/BlackFlagDAO/status/1892272691278721106
“We took a step back and said ‘OK, let’s invent the transistor for the quantum age. What properties does it need to have?"
Returning to first principles to design the next quantum chip. I like it!
https://news.microsoft.com/source/features/ai/microsofts-majorana-1-chip-carves-new-path-for-quantum-computing/
Returning to first principles to design the next quantum chip. I like it!
https://news.microsoft.com/source/features/ai/microsofts-majorana-1-chip-carves-new-path-for-quantum-computing/
Be Ettore Majorana.
Predict particles that are their own antiparticles
Mysteriously vanish (maybe met your own antiparticle)
Have a fermion and a quantum computing processor named after you
Live forever in superposition.
https://cerncourier.com/a/ettore-majorana-genius-and-mystery/
Predict particles that are their own antiparticles
Mysteriously vanish (maybe met your own antiparticle)
Have a fermion and a quantum computing processor named after you
Live forever in superposition.
https://cerncourier.com/a/ettore-majorana-genius-and-mystery/
One of the reasons I love him is that he goes so far down the rabbit hole for “what ifs”. My kind of hyperfixation https://youtu.be/dFVrncgIvos?si=utCg9hEOCkRqM3Rw
Biological artificial intelligence on the horizon 👀
6015
Ayan
@gmo·22:00 18/02/2025
no longer building unicorn companies in /synbio we’ve moved on to literally engineering unicorns
This is not a drill!
This team plans to create artificial biological intelligence by 2030 🦄 🧬
possibly the end for us, but at least we’re going out weird
https://x.com/josiezayner/status/1891870475212496947
This is not a drill!
This team plans to create artificial biological intelligence by 2030 🦄 🧬
possibly the end for us, but at least we’re going out weird
https://x.com/josiezayner/status/1891870475212496947
Wanna fund science the right way?
STOP PROPPING UP FOR-PROFIT PUBLISHERS
https://www.experimental-history.com/p/funding-science-is-actually-a-badass
STOP PROPPING UP FOR-PROFIT PUBLISHERS
https://www.experimental-history.com/p/funding-science-is-actually-a-badass
It looks like we can time travel backwards? 🤯
This paper recently published thinks that at quantum levels systems can go forward and backward, which is amazing.
"This discovery provided a mathematical foundation for the idea that time-reversal symmetry still holds in open quantum systems — suggesting that time's arrow may not be as fixed as we experience it... The research offers a fresh perspective on one of the biggest mysteries in physics. Understanding the true nature of time could have profound implications for quantum mechanics, cosmology and beyond."
https://www.nature.com/articles/s41598-025-87323-x
This paper recently published thinks that at quantum levels systems can go forward and backward, which is amazing.
"This discovery provided a mathematical foundation for the idea that time-reversal symmetry still holds in open quantum systems — suggesting that time's arrow may not be as fixed as we experience it... The research offers a fresh perspective on one of the biggest mysteries in physics. Understanding the true nature of time could have profound implications for quantum mechanics, cosmology and beyond."
https://www.nature.com/articles/s41598-025-87323-x
Recording an episode soon with the Molecule.xyz and Pump.science guys.
My first question: 'Is Desci a scam. Help me understand why not'.
What else would you guys like to ask?
(P.S.: Top 3 questions get a shout-out on the pod)
My first question: 'Is Desci a scam. Help me understand why not'.
What else would you guys like to ask?
(P.S.: Top 3 questions get a shout-out on the pod)
Some of last year’s key developments in computer science, covered by Quanta Magazine. Including (not too surprisingly) advancements in LLMs and Quantum —
https://www.quantamagazine.org/the-year-in-computer-science-20241219/
https://www.quantamagazine.org/the-year-in-computer-science-20241219/
"a team at Oxford University describes using quantum teleportation to link two pieces of quantum hardware that were located about 2 meters apart, meaning they could easily have been in different rooms entirely. Once linked, the two pieces of hardware could be treated as a single quantum computer, allowing simple algorithms to be performed that involved operations on both sides of the 2-meter gap"
https://www.nature.com/articles/s41586-024-08404-x
https://www.nature.com/articles/s41586-024-08404-x
"may contribute fresh ideas on how to achieve reliable approaches to quantum computing or reveal ways to develop room-temperature superconduction..."
https://science.slashdot.org/story/25/02/08/227213/twisted-graphene-sheets-reveal-unconventional-superconductivity-governed-by-quantum-geometry?utm_source=rss1.0moreanon&utm_medium=feed
https://science.slashdot.org/story/25/02/08/227213/twisted-graphene-sheets-reveal-unconventional-superconductivity-governed-by-quantum-geometry?utm_source=rss1.0moreanon&utm_medium=feed