DNA, Genomics, Bioinformatics 🧬

/dna58

All things DNA. Genomics, Bioinformatics, Genetic Engineering, Bioethics +

Fine-tuning Llama 3.1, researchers at MBZUAI built BiMediX2, an Arabic-English VLM for medical use cases that excels in both text and visual tasks — including interpreting medical images from X-Rays, CT scans, MRIs and more.
The models and datasets will be available publicly on Hugging Face.

https://www.threads.net/@aiatmeta/post/DDsBgdjSZOu?xmt=AQGzc7UBV0Z5GiAXQKSFZyLQ87pn-t223H0kUIU7zzX0vw
GDDA v0.21 XP utilizing ARPA's Subatomic Investigation Engine. 🧬🔍

Two agents working together to analyze DNA, RNA, PROTEIN sequences, or fasta files, providing an in-depth report on the specimen.

Fast rev comps, transcription, translation, anomaly and k-mer analysis, homology based on 3 public databases and datasets and a patent analyser to check for provided sequence in published patents.

Can you see this as the backbone for a biosecurity play?
"The bridge recombinase mechanism, a precise and powerful tool to recombine and rearrange DNA in a programmable way. Going far beyond programmable genetic scissors like CRISPR, the bridge recombinase mechanism enables scientists to specify not only the target DNA to be modified, but also the donor material to be recognized, so they can insert new, functional genetic material, cut out faulty DNA, or invert any two sequences of interest"
https://scitechdaily.com/a-word-processor-for-genes-scientists-unveil-fundamentally-new-mechanism-for-biological-programming/
There is a less known bug in a gene sequence, more specifically in an olfactory receptor called OR6A2, where if you have it, apparently some veggies taste like soap :D
How fast do you think this gen of AI Chips will handle biotech apps, eg. full genome sequencing, protein folding sims, etc? 🤔

https://www.cerebras.net/press-release/cerebras-announces-third-generation-wafer-scale-engine
The process involves genetically engineering white blood cells called T cells to create what’s known as chimeric antigen receptor (or CAR) T cells. These specialized cells recognize and attack a specific cellular target.

https://www.inverse.com/health/quest-reprogram-immune-cells-anti-aging-remedy
This guy edited the genes of two newborn babies to silence a gene sequence that gave them a big chance of carrying the HIV virus. The parents loved it, the University where he worked, and the Chinese govt didn't.

https://edition.cnn.com/2023/07/03/china/he-jiankui-gene-editing-proposal-china-intl-hnk-scn/index.html