242542
Omar
@dromar.eth #242542
Physician always trying to learn, passionate about healthspan and precision medicine.
omarsaleem.xyz
1490 Follower 203 Following
o3 always has a hard time updating Canvas for some reason
Congrats to $COIN
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Hello Kitty themed check-in area for EVA Air at TPE, Taiwan. One of my favorite airports in the world with impressive plane watching and airlines.
Taiwan as a city is underrated from what it offers. Especially hiking and natural beauty.
https://zora.co/coin/base:0x030d7cc80c8a6f2480564b78ed30b87dda168cad?referrer=0xa6a0e073303e1c1810b8b084698db2b8b654c946
Taiwan as a city is underrated from what it offers. Especially hiking and natural beauty.
https://zora.co/coin/base:0x030d7cc80c8a6f2480564b78ed30b87dda168cad?referrer=0xa6a0e073303e1c1810b8b084698db2b8b654c946
A couple of useful studies illustrating diabetics should be able to tolerate hypergravity from spaceflight. Will become more and more relevant as we near commercial space flight becoming ubiquitous.
https://asma.kglmeridian.com/view/journals/amhp/93/9/article-p688.xml
https://asma.kglmeridian.com/view/journals/amhp/96/2/article-p101.xml
https://asma.kglmeridian.com/view/journals/amhp/93/9/article-p688.xml
https://asma.kglmeridian.com/view/journals/amhp/96/2/article-p101.xml
Seeing lots of interest in Rapamycin internationally right now (dont know why, not the biggest fan).
PSA: if you are considering starting Rapamycin, and from a region or area where TB (tuberculosis) is endemic, please get tested first.
Otherwise, it's like putting gasoline on a matchstick.
PSA: if you are considering starting Rapamycin, and from a region or area where TB (tuberculosis) is endemic, please get tested first.
Otherwise, it's like putting gasoline on a matchstick.
It seems may be better waiting for the new Meta Ray Bans later this year. Not a for sure thing though: https://www.tomsguide.com/computing/smart-glasses/ray-ban-meta-glasses-just-tipped-for-game-changing-upgrade-in-2025
This. Glad someone articulated so well.
Having lived in Bushwick pre-gentrification into its early transition for 4 years in med school (as it was the only place I could afford) its crazy how people there think they're warehouse workers now.
My apartment mates were welders, struggling artists (living 4 to a room type). Then the last 2 years the apartment next door got a full renovation and finance folk moved in with some faux country living.
Not that gentrification is bad. But lets be real about it atleast...
Having lived in Bushwick pre-gentrification into its early transition for 4 years in med school (as it was the only place I could afford) its crazy how people there think they're warehouse workers now.
My apartment mates were welders, struggling artists (living 4 to a room type). Then the last 2 years the apartment next door got a full renovation and finance folk moved in with some faux country living.
Not that gentrification is bad. But lets be real about it atleast...
20384
basil (recession arc)
@itsbasil·2 days ago
also why does everyone in brooklyn cosplay as working class people these days 😭
you went to nyu, fully paid by daddy & bartend at a cocktail bar that serves $19 vodka sodas 😭
you went to nyu, fully paid by daddy & bartend at a cocktail bar that serves $19 vodka sodas 😭
Im now thinking if there is limited time before multimodal takes off and Ray Bans become the new iPhone. And if I should buy one.
4407
keccers
@keccers.eth·3 days ago
It’s weird because I personally have vouched for Meta Ray Bans 2x this week and gotten both people to buy them
Both times none of this slop crap was the draw
Person 1 was my brother. He wants to take more in the moment photos and videos of his baby daughter
Person 2 was my Russian neighbor. He wants to take videos on his motorcycle and show his mom back in Russia what American grocery stores are like without whipping out his phone
Both of these use cases feel very HUMAN
I am not going to say no one wants the slop but….
Both times none of this slop crap was the draw
Person 1 was my brother. He wants to take more in the moment photos and videos of his baby daughter
Person 2 was my Russian neighbor. He wants to take videos on his motorcycle and show his mom back in Russia what American grocery stores are like without whipping out his phone
Both of these use cases feel very HUMAN
I am not going to say no one wants the slop but….
So we now use a real ID that needs a manual magnifying glass for verification?
This also raises an interesting dilemma of who pays for the resulting treatments.
Having experienced both on the insurance and cash forms of treatment, the capacity and willingness of people to pay for tx, especially longevity, is severely overrated.
GLP-1s are a major exception, but too often are used as a rule.
Having experienced both on the insurance and cash forms of treatment, the capacity and willingness of people to pay for tx, especially longevity, is severely overrated.
GLP-1s are a major exception, but too often are used as a rule.
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I remember when Unity was touted as the blueprint for longevity research. Sadly many current companies will face this reality, but hopefully some reach their goals.
$700mil to $19mil to change
https://www.sfgate.com/tech/article/bay-area-biotech-company-lays-off-every-worker-20311477.php
$700mil to $19mil to change
https://www.sfgate.com/tech/article/bay-area-biotech-company-lays-off-every-worker-20311477.php
Hyatt adding Pelotons to almost all locations has been a blessing for my mitochondria.
Not at all a fan of Jumma khutbah being about India-Pakistan. Not the place, frankly.
There is no room for politics in any faith, why all faiths have a beauty and serenity to them.
There is no room for politics in any faith, why all faiths have a beauty and serenity to them.
If you drink a Monster, Celsius or Red Bull more than once a week, I would "guide" (as I cannot recommend) said person to use a wearable with an ECG. Especially if 40yo+
Seen far too many SVTs and other arrhythmias on those drinks.
Seen far too many SVTs and other arrhythmias on those drinks.
Part of me thinks, albeit reluctantly and (very) hesitantly, there are learnings for the crypto community to take from the recent growth in 'longevity' hype/adoption among the masses.
I have had a crazy amount of friends and family reach out about where they can do a Lp(a) or Dexa and then do it and come back to me asking what it means and how to improve. (which they then just do for a week and back to status quo)
A lot I think has to do with the more positive image the 'longevity' community has shaped itself to be vs the gambling of memecoins masquerading as utility.
As much as the 'next $-billion app is a toy' concept is true, it should also have some seriousness to it as well.
I have had a crazy amount of friends and family reach out about where they can do a Lp(a) or Dexa and then do it and come back to me asking what it means and how to improve. (which they then just do for a week and back to status quo)
A lot I think has to do with the more positive image the 'longevity' community has shaped itself to be vs the gambling of memecoins masquerading as utility.
As much as the 'next $-billion app is a toy' concept is true, it should also have some seriousness to it as well.
Didnt notice this Notion AI meeting notes block until today.
Facts
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"Freedom to most, it is an idea... an abstract thought that pertains to control. That's not freedom. That's independence. Freedom is riding wild over untamed land with no notion any moment exists beyond the one you are living." -1883
UA475 in classic ‘Friend Ship’ retro livery — channeling the 1970s mainline charm with JT8D-era vibes on an IAE-powered A320. A living tribute to United’s legacy at SFO
https://zora.co/coin/base:0xe34f9dee0461c7cb1de2c68d432100e8d4354c4f?referrer=0xa6a0e073303e1c1810b8b084698db2b8b654c946
https://zora.co/coin/base:0xe34f9dee0461c7cb1de2c68d432100e8d4354c4f?referrer=0xa6a0e073303e1c1810b8b084698db2b8b654c946
‘Celebrating India’ livery- Air India 777-300ER
https://zora.co/coin/base:0x87ce049e370a3794208f5570236896c976142703?referrer=0xa6a0e073303e1c1810b8b084698db2b8b654c946
https://zora.co/coin/base:0x87ce049e370a3794208f5570236896c976142703?referrer=0xa6a0e073303e1c1810b8b084698db2b8b654c946
A friend artist of mine. Highly recommend their work.
https://zora.co/coin/base:0x873f7b9e5ed74d70eb1e586c87c40a9bfceecd09?referrer=0xa6a0e073303e1c1810b8b084698db2b8b654c946
https://zora.co/coin/base:0x873f7b9e5ed74d70eb1e586c87c40a9bfceecd09?referrer=0xa6a0e073303e1c1810b8b084698db2b8b654c946
I love flying on planes. More than almost anything outside my family. The horizon views at daybreak and sunsets are some of my favorite times. Will start sharing more of these experiences on Zora.
https://zora.co/coin/base:0x61d6642e997de5356e018c64424b63eec7dc70cb?referrer=0xa6a0e073303e1c1810b8b084698db2b8b654c946
https://zora.co/coin/base:0x61d6642e997de5356e018c64424b63eec7dc70cb?referrer=0xa6a0e073303e1c1810b8b084698db2b8b654c946
Wouldn’t be surprised to see many GLP-1 based economies struggle after May 21st once compounding goes away.
This includes many ‘Longevity’ companies whose main source of revenue are compounded GLP-1 meds.
This includes many ‘Longevity’ companies whose main source of revenue are compounded GLP-1 meds.
From a friend running a physical B2C business was early to FB Groups and TikTok and now saying social media ROI is dead...just when I start posting on LinkedIn and TikTok
Something poetic in the fanbases of Milan and Paris.
Refreshing.
Refreshing.
CBS just stopped coverage of the PSG-Arsenal game…for black smoke
Asking for a friend, I have no musical acumen (Dave Matthews Band and Kenny Chesney radios have been stuck on my YT Music for more than a decade):
What is the best way to share music on @farcaster?
What is the best way to share music on @farcaster?
just tipped my favorite farcasters!
thank you @osama @keccers.eth @kaufman @aviationdoctor.eth @ryangrim for being here :)
thank you @osama @keccers.eth @kaufman @aviationdoctor.eth @ryangrim for being here :)
HIPAA, in its current form, is the biggest barrier to keeping the US health system at par with the rest of the world.
The layers of red tape it adds are beyond imagination. And reinforced by a thriving economy of middlemen who meet at seemingly weekly health conferences with patient money.
The layers of red tape it adds are beyond imagination. And reinforced by a thriving economy of middlemen who meet at seemingly weekly health conferences with patient money.
If there was any doubt on Airbus' dominance. Especially with the A330Neo and A321 garnering such high demand.
Makes sense for Boeing to want to increase 737Max production capacity.
cred: Coby Explains
Makes sense for Boeing to want to increase 737Max production capacity.
cred: Coby Explains
Surprising how little activity @researchhubf has on here. A research paper mini-app would be powerful as a tool for sharing papers and providing minting capability for viewing.
Also if peer-reviews/comments can be enabled.
Also if peer-reviews/comments can be enabled.
Found an o1-preview study that did a great job breaking down the various strengths o1 had over previous completion models. Primarily, as expected the gains are in differential development which is great to see. And management reasoning was much improved as well. Also the b&w low variability seen below is a sight to behold. Big move forward.
Next step will be to see this in clinical setting since most differentials/management falls apart after day 1 in real life. How it adapts and adjusts to that. In my own experience, it has struggles some there, but hope it continues to improve. Exciting to see.
https://arxiv.org/abs/2412.10849v1
Next step will be to see this in clinical setting since most differentials/management falls apart after day 1 in real life. How it adapts and adjusts to that. In my own experience, it has struggles some there, but hope it continues to improve. Exciting to see.
https://arxiv.org/abs/2412.10849v1
This has to be one of the best football games in the history of the Champions league.
Quality of all 6 goals is 8+
Quality of all 6 goals is 8+
This Barća team is special
The worst lead to have in football is 2-0
Golazo Lamine Yamal!
The growing confusion of longevity trends for new patients. Upsells everywhere.
Gemini Veo 2 is neat
Gemini Veo 2 is neat
Waymo + Lean six sigma could be a good combo
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Halfway through and the perspective on just how new learning structures are makes me more certain that we are in for a ride when it comes to learning and knowledge.
Medical education and institutions, likely alongside the Manhattan project and NASA, are likely the two biggest contributions of the American knowledge. Going forward, this will likely shift away from institutions to others of a parallel or greater size.
Medical education and institutions, likely alongside the Manhattan project and NASA, are likely the two biggest contributions of the American knowledge. Going forward, this will likely shift away from institutions to others of a parallel or greater size.
Etihad has quietly become one of the greatest turnaround stories in the history of aviation the last 15 years.
IPO imminent and demand likely will be high.
IPO imminent and demand likely will be high.
Would Etsy be a beneficiary of this?
I guess the original items are still sourced from China
I guess the original items are still sourced from China
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PSG playing like they’re a PlayStation Game
Patients who had >4 address changes in study’s 6 year span had a 65.2% increased risk of psychiatric illness.
New study using EHR data for social determinants.
Vs 27.7% risk in 0 address changes.
Digital nomads qualify?
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0318552
New study using EHR data for social determinants.
Vs 27.7% risk in 0 address changes.
Digital nomads qualify?
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0318552
Practitioner is the new 'Provider'. Got called that today.
I didnt answer. I dont answer to either.
I didnt answer. I dont answer to either.
As someone who has moved 3 countries, irony is that it is all the more important to be a global citizen in a de-globalized world.
Portability will matter as geopolitics becomes shaken and fluid.
https://x.com/RayDalio/status/1916967796065423688
Portability will matter as geopolitics becomes shaken and fluid.
https://x.com/RayDalio/status/1916967796065423688
Playing around with some AI based learning tools as I've gotten curious about it for my son.
Realized how much of a moat (and scary) this can be if built properly with memory and customization of a student's strength and weaknesses, from kindergarten to 12th to college (if that still exists).
Realized how much of a moat (and scary) this can be if built properly with memory and customization of a student's strength and weaknesses, from kindergarten to 12th to college (if that still exists).
He should be posting this on @paragraph.
https://open.substack.com/pub/chamath/p/deep-dive-a-primer-on-stablecoins?r=1fp8g&utm_medium=ios
https://open.substack.com/pub/chamath/p/deep-dive-a-primer-on-stablecoins?r=1fp8g&utm_medium=ios
As mitochondrial-derived peptides (MDPs) like MOTS-c emerge as promising therapies for metabolic diseases, a critical gap remains:
How do mitochondrial DNA (mtDNA) polymorphisms impact treatment responses in diverse populations?
East Asian studies reveal variants like m.1382A>C alter MOTS-c function and diabetes risk. Yet, South Asians-who face high rates of early-onset diabetes-are rarely included in mtDNA research. Without data on their unique haplogroups (e.g., M, R), we risk inequitable access to precision therapies.
Blog post on this later today! https://rotiandchai.substack.com/
How do mitochondrial DNA (mtDNA) polymorphisms impact treatment responses in diverse populations?
East Asian studies reveal variants like m.1382A>C alter MOTS-c function and diabetes risk. Yet, South Asians-who face high rates of early-onset diabetes-are rarely included in mtDNA research. Without data on their unique haplogroups (e.g., M, R), we risk inequitable access to precision therapies.
Blog post on this later today! https://rotiandchai.substack.com/
